Endocrine Abstracts

Hypothalamic regulation of the appetite and reproductive neuroendocrine axes is modulated by nutritional feedback from the periphery, potentially via shared mechanisms. Ghrelin is a recently identified orexigenic hormone secreted by the stomach that has been implicated in meal-time hunger, energy homeostasis and body weight regulation. In rodents, intracerebroventricular (ICV) injection acutely stimulates food intake and one study has shown that it can also transiently suppres...